New Preprints


22. H Chajjer, VA Rizvi and R Roy, "Life cycle process dependencies of positive-sense RNA viruses suggest strategies for inhibiting productive cellular infection" Journal of the Royal Society Interface, (2021)

21. S Jagtap, et al., "Evaluation of spike protein antigens for SARS-CoV-2 serology" Journal of Virological Methods, 296, 114222 (2021)

20. J Panwar and R Roy, "Integrated Field's metal microelectrodes based microfluidic impedance cytometry for cell-in-droplet quantification" MicroE Engineering, doi: (2019)

19. S Umrao, Anusha S, V Jain, B Chakraborty, R Roy, "Smartphone-based kanamycin sensing with ratiometric FRET" RSC Advances, 9, 6143-6151 (2019)

18. M Kar, A Nisheetha, A Kumar, S Jagtap, J Shinde, M Singla, S Marimuthu, A Pandit, A Chandele, SK Kabra, S Krishna, R Roy, R Lodha, C Pattabiraman, G Medegeshi, "Isolation and molecular characterization of Dengue virus clinical isolates from pediatric patients in New Delhi" International Journal of Infectious Diseases, pii:S1201-9712(18)34953-1 (2019)


17. P Sathyanarayana, S Maurya, ABehera, M Ravichandran, SS Visweswariah, KG Ayappa, and R Roy, "Cholesterol promotes Cytolysin A activity by stabilizing the intermediates during pore formation" PNAS (USA), 115 (31) E7323-E7330, (2018)

16. S Banerjee, S Maurya and R Roy, “Single-molecule fluorescence imaging: generating insights into molecular interactions in virologyJ Biosciences, 43(3), 519-540, doi: 10.1007/s12038-018-9769-y (2018)

15. S Baral, R Roy, NM Dixit, “Modelling how reversal of immune exhaustion elicits cure of chronic hepatitis C after the end of treatment with direct-acting antiviral agentsImmunology & Cell Biology, 96(9), 969-980, doi: 10.1111/imcb.12161 (2018)

14. HR Koh, R Roy, M Sorokina, GQ Tang, D Nandakumar, SS Patel, T Ha, "Correlating Transcription Initiation and Conformational Changes by a Single-Subunit RNA Polymerase with Near Base-Pair Resolution" Molecular Cell, 70(4): 695-706, doi: 10.1016/j.molcel.2018.04.018 (2018)

13. S Umrao, V Jain, Anusha, B Chakraborty, R Roy, "Protein-induced fluorescence enhancement as aptamer sensing mechanism for thrombin detection." Sensors and Actuators B: Chemical 267: 294-301 doi: (2018)

12. GQ Tang, D Nandakumar, RP Bandwar, KS Lee, R Roy, T Ha and SS Patel, "Relaxed Rotational and Scrunching Changes in P266L Mutant of T7 RNA Polymerase Reduce Short Abortive RNAs while Delaying Transition into Elongation" PLoS One, 9(3): e91859. doi:10.1371/journal.pone.0091859 (2014)

11. ZW Zhao*, R Roy*, JCM Gebhardt*, DM Suter*, AR Chapman and S Xie, "Spatial organization of RNA polymerase II inside a mammalian cell nucleus revealed by reflected light-sheet super-resolution microscopy" PNAS (USA), 111(2):681-6 (2014) * equal contribution

10. R Roy, "Next generation optical microscopy" Current Science, 105(11):1524-36 (2013)

9. JCM Gebhardt, DM Suter, R Roy, ZW Zhao, AR Chapman, S Basu, T. Maniatis and S Xie, “Single-molecule imaging of transcription factor binding to DNA in live mammalian cellsNature Methods, 10(5):421-6(2013)


8. R Zhou, A Kozlov, R Roy, J Zhang, S Korolev, T Lohman and T Ha, “SSB Functions as a Sliding Platform that Migrates on DNA via ReptationCell, 146(2): 222-32 (2011)

  • Featured with the issue’s PaperFlick

7. G Tang, R Roy, T Ha and S Patel, “Kinetics of Transition to Elongation Phase by T7 RNA PolymerasePNAS (USA), 106(52): 22175-80 (2009)

6. R Roy, A Kozlov, T Lohman and T Ha, “Rolling Migration of SSB Stimulates RecA Filament FormationNature, 461(7267): 1092-7 (2009)

  • Accompanying Comment in News and Views Nature, 461(7267):1067-8 (2009)

5. W Min, S Lu, S Chong, R Roy, G Holtom and S Xie, “Imaging Chromophores with Non-Detectable Fluorescence by Stimulated Emission MicroscopyNature, 461(7267): 1105-9 (2009)

  • Featured Article of the Nature issue; Accompanying Comment in News and Views Nature, 461(7267):1069-70 (2009)

  • Eisenstein, Michael, "Seeing in the dark" Nature Methods 6: 866 (2009)

  • Borman, Stu, "Seeing Molecules With A New Light" C&E News (October 21, 2009)

  • ‘Must Read’ Article rating at (Ebbinghaus S, Gruebele M: 2009.

4. G Tang, R Roy, T Ha and S Patel “Transcription initiation in a single-subunit RNA polymeraseproceeds through DNA scrunching and rotation of the N-terminal subdomainsMolecular Cell, 30(5): 567-77 (2008)

3. R. Roy, S. Hohng and T Ha “A practical guide to single molecule FRETNature Methods, 5(6): 507-18 (2008)

  • Nature ‘Milestones in Light Microscopy’ Collection Article

2. R Roy, A Kozlov, T Lohman and T Ha, "Dynamic structural rearrangements between DNA binding modes of E. coli SSB protein", Journal of Molecular Biology, 369(5):1244-57 (2007)

1. V Arluison, S Hohng, R Roy, O Pellegrini, P Regnier and T Ha, "Spectroscopic observation of RNA chaperone activities of Hfq in post-transcriptional regulation by a small non-coding RNA", Nucleic Acids Research, 35(3):999-1006 (2007)

  • ‘Recommended’ Article rating at (Westhof E: 2007.