Open Positions

Laboratory Technician or Project Assistant (This position has been filled)

We are excited to announce a new opening for a Laboratory Technician or Project Assistant for an ongoing project on Multiplexed Serology Surveillance. The successful candidate will play a crucial role in antigen design, generation, and validation, preparation of Luminex bead reagents, and conducting validation ELISAs.

Key Responsibilities:

• Design, generate, and validate antigens for multiplex serology surveillance.

• Prepare Luminex bead reagents as per the project requirements.

• Conduct validation ELISAs ensuring the accuracy of results.

• Analyze data, report and document results, and make modifications as necessary.

• Participate in the planning, organization, and management of the lab and research project.

• Assist in the development and optimization of standard operating procedures.

• Ensure compliance with all safety guidelines, including handling and disposal of waste according to safety procedures.

• Collaborate with the project team, providing support and coordination to achieve project objectives.

• Other duties as assigned by the Project Leader or Principal Investigator.

Qualifications:

• A bachelor’s degree in biology, chemistry, molecular biology, or a related field.

• Prior experience working in a lab environment, preferably with Luminex or ELISA technology.

• Proficiency in handling and preparation of antigens including protein expression (bacteria and/or mammalian), molecular biology including cloning, protein purification, etc.

• Knowledge of standard lab safety procedures and regulations.

• Demonstrated ability to work both independently and collaboratively within a team.

• Excellent oral and written communication skills.

• Strong organizational skills and the ability to manage multiple tasks concurrently.

Preferred:

• Experience with automated liquid handing or high throughput synthetic biology.

• Experience with multiplex serology surveillance or a related project is useful but not necessary.

• GATE or CSIR-NET qualified

Salary: Based on experience and eligibility. 

Application: To apply, please submit your CV, a brief cover letter detailing your interest and qualifications for the role and contact information for two professional references. Email directly to Rahul Roy.

This position has been filled. 

Job Title: Project Associate – Strategizing antiviral therapy against Flaviviruses 

Location: Department of Chemical Engineering, Indian Institute of Science, Bangalore 

Position Type: Full-time 

Job Description: 

We are seeking motivated and talented graduates to join our team, to develop novel antiviral strategies against Dengue and Zika virus infection. This position offers an exciting opportunity to be part of cutting-edge research in quantitative virology, systems biology, molecular biology, and cell biology. 

You will play a key role in designing and conducting experiments to study the effects of antiviral drugs at the early life cycle stage of Flaviviral infections in mammalian cells, exploring strategies predicted by our recent work [1]. This role is ideal for recent graduates looking to expand their experience in a dynamic and highly collaborative environment. 

[1] Chhajer H., Rizvi V. A. and Roy R., 2021. Life cycle process dependencies of positive-sense RNA viruses suggest strategies for inhibiting productive cellular infection J. R. Soc. Interface.1820210401
 

Key Responsibilities: 

• Culture and maintain various mammalian cell lines under sterile conditions. 

• Perform routine cell biology techniques such as cell transfection, cell viability assays, and imaging. 

• Perform viral infection assays on mammalian cell lines (e.g., plaque assays and viral growth curves).  

• Evaluate the impact of viral infections on cellular processes through molecular biology methods (e.g., qPCR, Flow analysis, immunofluorescence, etc.). 

• Assist in testing and optimizing antiviral compounds using high-throughput screening platforms. 

• Collect, analyze, and interpret experimental data. 

• Document experimental procedures and results in laboratory notebooks, maintaining accurate records. 

• Collaborate with team members and contribute to scientific discussions. 

• Ensure compliance with biosafety and laboratory safety guidelines. 

Desired Qualifications: 

• Education: Bachelor’s or Master’s degree in biotechnology, molecular biology, virology, microbiology, cell biology, biotechnology, or related field. 

• Experience: Previous hands-on experience in cell culture, viral assays, or related molecular biology techniques is preferred. 

• Technical Skills: 

• Expertise in culturing mammalian cells. 

• Experience with viral infection models and assays. 

• Proficiency in basic molecular biology techniques like PCR, FACS, immunostaining (desirable). 

• Knowledge of biosafety practices when handling infectious agents. 

• Problem-solving Skills: Highly organized, detail-oriented, and capable of troubleshooting experimental challenges. 

• Collaborative Attitude: Enthusiastic about working in a multidisciplinary team and sharing scientific knowledge. 

Benefits: 

• Competitive salary as per IISc norms. 

• Opportunities for career development and advancement. 

• Access to state-of-the-art research facilities and equipment. 

• Collaborative and supportive research environment. 

How to Apply: 

Please submit your resume, a cover letter detailing your research experience and interest in viral infection studies, and contact information for two references to rahulroy@iisc.ac.in. Applications will be reviewed on a rolling basis until the position is filled. 

Join us in advancing scientific knowledge on viral infections and contribute to impactful research that drives new therapeutic discoveries! 

Applications will be accepted until Dec 31, 2024, but the position may be filled before this date.