Our understanding of most biological processes comes from ensemble studies of the molecules carried out in a tube or using reporters in cells and organisms. Such mechanistic understanding of biological phenomena is complicated by

How do events taking place at the level of single molecule translate to biologically significant phenomena?

Our lab leads an interdisciplinary research program that aims to innovate and engineer technologies to help understand this basic question. We primarily focus on long-standing questions in infectious diseases caused by positive strand RNA viruses and pathogenic bacteria using single molecule detection, quantitative genomics and high-resolution imaging.

Such understanding of pathogen biology and host-pathogen interactions will help us design new drugs, vaccines and intervention strategies against several infectious diseases including Dengue.  

To learn more, please read our research interests.

Our laboratory is located in the Department of Chemical Engineering at the Indian Institute of Science, Bangalore, India. We are also associated with the Centre for BioSystems Science and Engineering at IISc. Directions to the lab can be found here.

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Last Major Updated: 17th March 2019