Publications

   2014                                                                                                                                     

12. GQ Tang, D Nandakumar, RP Bandwar, KS Lee, R Roy, T Ha and SS Patel, "Relaxed Rotational and Scrunching Changes in P266L Mutant of T7 RNA Polymerase Reduce Short Abortive RNAs while Delaying Transition into Elongation" PLoS One, 9(3): e91859. doi:10.1371/journal.pone.0091859 (2014)                                 
                                                                                                           
11.  ZW Zhao*, R Roy*, JCM Gebhardt*, DM Suter*,  AR Chapman and S Xie, "Spatial organization of RNA polymerase II inside a mammalian cell nucleus revealed by reflected light-sheet super-resolution microscopy" PNAS (USA), 111(2):681-6 (2014)  * equal contribution

   2013                                                                                                                                                                                                                                                                                                               
10.  R Roy, "Next generation optical microscopy" Current Science, 105(11):1524-36 (2013)

9. JCM Gebhardt, DM Suter, R Roy, ZW Zhao, AR Chapman, S Basu, T. Maniatis and S Xie, Single-molecule imaging of transcription factor binding to DNA in live mammalian cells Nature Methods, 10(5):421-6 (2013)


   Pre-2012                                                                                                                                                             

8.  R Zhou, A Kozlov, R Roy, J Zhang, S Korolev, T Lohman and T Ha, “SSB Functions as a Sliding Platform that Migrates on DNA via ReptationCell, 146(2): 222-32 (2011)

v  Featured with the issue’s PaperFlick


7.  G Tang, R Roy, T Ha and S Patel, “Kinetics of Transition to Elongation Phase by T7 RNA PolymerasePNAS (USA), 106(52): 22175-80 (2009)


6. R Roy, A Kozlov, T Lohman and T Ha, “Rolling Migration of SSB Stimulates RecA Filament FormationNature, 461(7267): 1092-7 (2009)

v  Accompanying Comment in News and Views Nature, 461(7267):1067-8 (2009)


5. W Min, S Lu, S Chong, R Roy, G Holtom and S Xie, “Imaging Chromophores with Non-Detectable Fluorescence by Stimulated Emission MicroscopyNature, 461(7267): 1105-9 (2009)

v  Featured Article of the Nature issue; Accompanying Comment in News and Views Nature, 461(7267):1069-70 (2009)

v  Eisenstein, Michael, "Seeing in the dark" Nature Methods 6: 866 (2009)

v  Borman, Stu, "Seeing Molecules With A New Light" C&E News (October 21, 2009)

v  ‘Must Read’ Article rating at F1000.com (Ebbinghaus S, Gruebele M: 2009. F1000.com/1166582)


4. G Tang, R Roy, T Ha and S Patel “Transcription initiation in a single-subunit RNA polymeraseproceeds through DNA scrunching and rotation of the N-terminal subdomainsMolecular Cell, 30(5): 567-77 (2008)


3.  R. Roy, S. Hohng and T Ha “A practical guide to single molecule FRETNature Methods, 5(6): 507-18 (2008)

v  Nature ‘Milestones in Light Microscopy’ Collection Article


2. R Roy, A Kozlov, T Lohman and T Ha, "Dynamic structural rearrangements between DNA binding modes of E. coli SSB protein", Journal of Molecular Biology, 369(5):1244-57 (2007)


1.  V Arluison, S Hohng, R Roy, O Pellegrini, P Regnier and T Ha, "Spectroscopic observation of RNA chaperone activities of Hfq in post-transcriptional regulation by a small non-coding RNA", Nucleic Acids Research, 35(3):999-1006 (2007)

v  ‘Recommended’ Article rating at F1000.com (Westhof E: 2007. F1000.com/1071893)